RNA Design Services
End-to-end computational consulting — from exploratory analysis to publication-ready results.
RNA Structure Consultancy
MFE folding, partition functions, base pair probabilities, and ensemble diversity analysis tailored to your RNA system. Co-transcriptional folding pathway analysis using DrTransformer and BarMap. Energy landscape construction to characterise metastable states and transition rates. 3D modelling with SimRNA and Amber. Custom pipeline development with the ViennaRNA Python API. Available to academic labs, biotech, and pharma R&D.
De Novo RNA Design
Computational design of functional RNA elements including xrRNA resistance structures, PRF-inducing pseudoknots, riboswitches, and synthetic mRNA constructs. Inverse folding with RNAinverse and advanced design with Infrared. Designs are delivered with a predicted folding ensemble and a wet-lab validation strategy, so experimental teams know exactly what to test.
ViennaRNA Training
Foundations workshop (4 h, online): RNA secondary structure basics, RNAfold, base pair probability analysis, and practical pipeline design. Suited for experimentalists and graduate students entering computational RNA biology.
Advanced workshop (full day): Energy landscapes, kinetic and co-transcriptional folding, Barriers, Kinfold, and ViennaRNA Python API scripting. Designed for computational biologists who want to go beyond single-structure prediction.
Custom in-lab training is available on request and can be adapted to your group's specific tools, workflows, and research questions.
Engagement Models
Advisory Call
A focused 60-minute session to review your RNA problem, interpret results, or map out a computational strategy. Ideal before committing to a larger project.
- 60-minute video call
- Written summary provided
- Follow-up Q&A via email
Project Retainer
Ongoing access to deep computational analysis — structured as a monthly retainer. Covers analysis, pipeline development, and regular check-ins.
- Defined monthly deliverables
- Priority turnaround
- Slack or email async support
- Monthly progress report
Research Collaboration
Co-authorship on research projects where deep computational RNA expertise is integral — from grant application through manuscript submission.
- Joint experimental design
- Manuscript co-authorship
- Grant writing support